In this weeks Journal symptoms of asthma.
Co-cultured Schwann cells from skin precursorsThe hunt continues for more available sources of neural stem cells. In this week’s Journal, McKenzie et al. Go to the skin as a source of neural crest precursors symptoms of asthma . If the authors rodent and human skin-derived precursor treated with forskolin differentiated and neuregulin-1a, a part of the cells in the Schwann cells. The authors then co-cultured rodent SKP-derived Schwann cells with with yellow fluorescent protein , with dorsal root ganglion neurons lacking from shiverer mice, myelin basic protein. After 3 weeks in vitro, most of the tagged Schwann cells were associated with axons many took on a myelinating phenotype, and some proliferate, apparently in response to axonal signals derived. YFP-tagged, SKP-derived Schwann cells in the sciatic nerve or brain shiverer mice transplanted successfully myelinated axons. Significantly naive human SKPs differentiated injured peripheral nerves or for newborn mouse brain neonatal shiverer mice brains in vivo and compact myelin is formed transplanted. ###Ian A. McKenzie, Jeff Biernaskie, Rajiv Midha and Freda D. (more…)