It is one of the reasons why it is so difficult to develop vaccines against HIV and malaria.
Are ‘invisible’to the immune system that microorganisms to vary a large capacity surface structure surface structure have known. It is one of the reasons why it is so difficult to develop vaccines against HIV and malaria, and why new flu However produced every year. However, it seems that these microorganisms are also able to completely avoid activation attacked a strong immune response in the person. This is what Professor Gunnar Lindahl from Lund University and his research group show in an article in Cell Host & Microbe – .
Tal toxic shock syndrome and a very serious autoimmune disease.The part of the bacteria, which has been studied , a surface protein called the M protein, or more precisely the part of the protein , which vary the ability to to escape attack must. The studies showed that the relevant portion of the protein extract was variable, variable, but also managed to not have a strong antibody reaction of the immune system. ‘That may be what actually the microorganisms ‘ main weapon: that they begin to avoid antagonizing the immune system in case of persistent infection, the immune system actually produce antibodies eventually, but then. (more…)