Med caverta .Sc., Lisa D. Edwards, Ph.D., Paul D. Scanlon, M.D., Julie C. Yates, B.S., Alvar Agusti, M.D., Ph.D., Per Bakke, Ph.D., Peter M.A. Calverley, M.B., Ch.B., M.D., Bartolome Celli, M.D., Harvey O. Coxson, Ph.D., Courtney Crim, M.D., David A. Lomas, M.D., Ph.D., William MacNee, M.B., Ch.B., M.D., Bruce E. Miller, Ph.D., Edwin K. Silverman, M.D., Ph.D., Ruth Tal-Singer, Ph.D., Emiel Wouters, M.D., Ph.D., and Stephen I. Rennard, M.D. For the ECLIPSE Investigators: Changes in Forced Expiratory Quantity in 1 Second over Time in COPD Since the seminal study by Fletcher et al. In the 1970s,1,2 it’s been widely recognized that chronic obstructive pulmonary disease is characterized by an accelerated decline in pressured expiratory quantity in 1 second .
All of the soldiers underwent extensive evaluation of occupational and environmental exposures. Of these soldiers, 49 were referred for video-assisted thoracoscopic lung biopsy at the discretion of the treating physician. The rest of the 31 soldiers were not known for biopsy for the good reasons outlined in Figure 1. The 38 soldiers who had biopsy results of constrictive bronchiolitis are the focus of this evaluation. We compared the results on pulmonary-function and cardiopulmonary-exercise screening for these soldiers with results for historical army control topics.9 We updated all medical histories, evaluation of symptoms, and disability ratings of the complete band of 80 soldiers through a survey in the fall of 2010.