There were no significant distinctions between your two groups with respect to baseline characteristics . Primary Analysis Regarding to Randomized Treatment Group As of January 13, 2009, with 226 eligible individuals enrolled and randomly assigned to a treatment group and 83 of the expected 137 occasions reported , the COG data and basic safety monitoring committee determined that the analysis met the criteria for early stopping of the randomization, based on the superiority of immunotherapy over regular therapy with regard to event-free survival .).02 without adjustment for interim analyses) .Investigators recruited one band of 11 congenitally blind and 15 normal-sighted participants from Italy another group of 18 congenitally blind and 18 normal-sighted participants from Denmark. They carried out three experiments. The initial compared pain thresholds and responses to suprathreshold discomfort stimuli among users of both groups. The second measured detection thresholds for warmth and cool perceptions. The third tested whether study outcomes could be reproduced within an independent study people with culturally distinct ways of responding to pain. Researchers used thermal probes on the medial forearm to measure thresholds of pain.