Eva van der Wall structure.
Randomization Computer-generated randomization was performed in blocks of 6, each containing a sequence of the three antibiotic strategies. Hospitals were assigned with their sequence after authorization of the analysis by a healthcare facility antibiotic committee. Two hospitals that had closely collaborating medical personnel were randomized as you cluster. All the hospitals prepared to participate until the calculated sample size was fulfilled or for a maximum of 2 years . Outcomes The primary outcome was all-cause mortality within 3 months after admission. The secondary outcomes were the time to starting oral treatment, length of hospital stay, and occurrence of minor or major complications through the hospital stay. (more…)