It is clear that the two need each other to operate as mobile mechanosensor.
The researchers repeated the experiment using cells developed to lack myosin II and then again with cells without cortexillin I. They discovered that I reacted cortexillin deformation unless myosin II was removed and myosin II responded to deformation unless cortexillin I was removed. – ‘It is clear that the two need each other to operate as mobile mechanosensor, ‘Robinson says.
Robinson, Associate Professor of Cell Biology, Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine.. With genetically modified mice, the team found that simply eliminate error causing the infection is not enough to restore an animal’s immune function. Or LPS or LPS, the dominant bacterial signal molecule which heralds the invasion must be inactivated. The results will appear in Cell Host & Microbe online. – We think this is the first evidence that the killing of the pathogens of bacterial infection is not enough for an animal to recover fully, said Dr. (more…)