Systemic Lupus affects an estimated 1.
Systemic Lupus affects an estimated 1.5 million Americans, mostly women, and about half have kidney damage. In systemic lupus attacks the normally protective immune system, the body’s organs damaging kidneys, blood or skin. Most people with lupus have achy or swollen joints, frequent fevers and prolonged or extreme fatigue. In comparison with kidney disease decreased SAHA spleen size in the mice and in the same time the production of certain T-cells decreased , key to the key to the autoimmune disease, in comparison with mice with lupus who can not get the drug. Also reduces excess protein in the urine in mice. – ‘Further studies are needed to delineate the most effective therapeutic regimen, ‘Mishra and seven colleagues reported in the article.
News & World Report.. The drug, SAHA , the onset of lupus – related kidney disease in mice with lupus inhibited said Nilamadhab Mishra, assistant professor of internal medicine – rheumatology, writing in the 15th September issue of The Journal of Immunology, published online today.
Mishra colleagues in the study included Christopher M. From Virginia – Maryland Regional College of Veterinary Medicine at Virginia Tech in Blacksburg, Virginia, Gilkeson MD, of the Medical University of South Carolina in Charleston, and scientists at the University of Miami Medical Center in Miami and Memorial Sloan – Kettering Cancer Center in New York. (more…)