The team noted.
An overall transmission rate of 43 per cent.. Was the result of the experiment – BSE and scrapie could be effectively transmitted between sheep by blood transfusion. Importantly, the team noted, the transmission could occur when blood was collected from donors before they developed signs of the disease, but was more likely in the later stages in the later stages of the infection. Of the 22 sheep who received infected blood from the BSE donor group, five showed signs of TSEs and three others showed evidence of infection without clinical signs, so. Overall transmission rate of 36 per cent Of the 21 infected scrapie recipients developed nine clinical scrapie, so.
Because the results were in line with what we are about human transmission helps the work to justify the control measures introduced to human blood supply. It also shows that blood of BSE – and scrapie-infected sheep could be used effectively not human experiments to answer important questions, such as the blood components are most heavily infected, and to develop much-needed diagnostic tests. .
Investigator noted that the results are consistent with what was obtained by the four cases of vCJD by blood transfusion in humans. In addition to the stage of infection in the donor such as genetic factors, variation in susceptibility to disease and the blood component transfused influence the transmission rate by transfusion in both sheep and humans.. (more…)